Eosinophil Granulocytes Account for Indoleamine 2,3-Dioxygenase-Mediated Immune Escape in Human Non Small Cell Lung Cancer

Eosinophil Granulocytes Account for Indoleamine 2,3-Dioxygenase-Mediated Immune Escape in Human Non Small Cell Lung Cancer

Indoleamine 2,3-dioxygenase (IDO), a catabolizing enzyme of tryptophan, is supposed to play a role in tumor immune escape. Its expression in solid tumors has not yet been well elucidated: IDO can be expressed by the tumor cells themselves, or by ill-defined infiltrating cells, possibly depending on...

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Bibliographic Details
Main Authors: Simonetta Astigiano, Barbara Morandi, Roberta Costa, Luca Mastracci, Antonella D'Agostino, Giovanni Battista Ratto, Giovanni Melioli, Guido Frumento
Format: Article
Language:English
Published: Elsevier 2005-04-01
Series:Neoplasia: An International Journal for Oncology Research
Subjects:
Non small cell lung cancer
indoleamine 2,3-dioxygenase
eosinophil granulocytes
immune escape
prognostic marker
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558605800703

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http://www.sciencedirect.com/science/article/pii/S1476558605800703

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