Rapid generation of microRNA sponges for microRNA inhibition.

Rapid generation of microRNA sponges for microRNA inhibition.

MicroRNA (miRNA) sponges are transcripts with repeated miRNA antisense sequences that can sequester miRNAs from endogenous targets. MiRNA sponges are valuable tools for miRNA loss-of-function studies both in vitro and in vivo. We developed a fast and flexible method to generate miRNA sponges and tes...

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Bibliographic Details
Main Authors: Joost Kluiver, Johan H Gibcus, Chris Hettinga, Annelies Adema, Mareike K S Richter, Nancy Halsema, Izabella Slezak-Prochazka, Ye Ding, Bart-Jan Kroesen, Anke van den Berg
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22238599/?tool=EBI

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