Retinal homeostasis and metformin-induced protection are not affected by retina-specific Pparδ knockout

Retinal homeostasis and metformin-induced protection are not affected by retina-specific Pparδ knockout

Peroxisome proliferator-activated receptors (PPARs) are a family of three nuclear hormone receptors (PPARα, PPARδ, and PPARγ) that are known to regulate expression of lipid metabolism and oxidative stress genes. Given their role in reducing oxidative stress in a variety of tissues, these genes are l...

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Bibliographic Details
Main Authors: Lei Xu, Emily E. Brown, Clayton P. Santiago, Casey J. Keuthan, Ekaterina Lobanova, John D. Ash
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:Redox Biology
Subjects:
Peroxisome proliferator-activated receptors
PPARδ
Retina
Metformin
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231720309058

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