Metalloproteinase inhibition prevents inhibitory synapse reorganization and seizure genesis
The integrity and stability of interneurons in a cortical network are essential for proper network function. Loss of interneuron synaptic stability and precise organization can lead to disruptions in the excitation/inhibition balance, a characteristic of epilepsy. This study aimed to identify altera...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2014-10-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996114001673 |