Altered white matter microstructure is associated with social cognition and psychotic symptoms in 22q11.2 microdeletion syndrome

Altered white matter microstructure is associated with social cognition and psychotic symptoms in 22q11.2 microdeletion syndrome

22q11.2 Microdeletion Syndrome (22q11DS) is a highly penetrant genetic mutation associated with a significantly increased risk for psychosis. Aberrant neurodevelopment may lead to inappropriate neural circuit formation and cerebral dysconnectivity in 22q11DS, which may contribute to symptom develop...

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Bibliographic Details
Main Authors: Maria eJalbrzikowski, Julio E. Villalon-Reina, Katherine H. Karlsgodt, Damla eSenturk, Carolyn eChow, Paul Matthew Thompson, Carrie E Bearden
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-11-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Schizophrenia
Theory of Mind
connectivity
DTI
psychosis
emotion recognition
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00393/full

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