Tissue-Resident Macrophages Limit Pulmonary CD8 Resident Memory T Cell Establishment

Tissue-Resident Macrophages Limit Pulmonary CD8 Resident Memory T Cell Establishment

Tissue resident memory CD8 T cells (TRM) serve as potent local sentinels and contribute significantly to protective immunity against intracellular mucosal pathogens. While the molecular and transcriptional underpinnings of TRM differentiation are emerging, how TRM establishment is regulated by other...

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Bibliographic Details
Main Authors: Nick P. Goplen, Su Huang, Bibo Zhu, In Su Cheon, Young Min Son, Zheng Wang, Chaofan Li, Qigang Dai, Li Jiang, Jie Sun
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-10-01
Series:Frontiers in Immunology
Subjects:
tissue-resident memory
alveolar macrophage
CD8 T cell differentiation
influenza
PPAR-γ
CD69
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.02332/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2019.02332/full

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