Association between amylin and amyloid-β peptides in plasma in the context of apolipoprotein E4 allele.

Association between amylin and amyloid-β peptides in plasma in the context of apolipoprotein E4 allele.

Amylin, a pancreatic peptide that readily crosses the blood brain barrier (BBB), and amyloid-beta peptide (Aβ), the main component of amyloid plaques and a major component of Alzheimer's disease (AD) pathology in the brain, share several features. These include having similar β-sheet secondary...

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Bibliographic Details
Main Authors: Wei Qiao Qiu, Max Wallack, Michael Dean, Elizabeth Liebson, Mkaya Mwamburi, Haihao Zhu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3919737?pdf=render

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http://europepmc.org/articles/PMC3919737?pdf=render

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