Bioengineering of a Full-Thickness Skin Equivalent in a 96-Well Insert Format for Substance Permeation Studies and Organ-On-A-Chip Applications

Bioengineering of a Full-Thickness Skin Equivalent in a 96-Well Insert Format for Substance Permeation Studies and Organ-On-A-Chip Applications

The human skin is involved in protecting the inner body from constant exposure to outer environmental stimuli. There is an evident need to screen for toxicity and the efficacy of drugs and cosmetics applied to the skin. To date, animal studies are still the standard method for substance testing, alt...

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Bibliographic Details
Main Authors: Katharina Schimek, Hao-Hsiang Hsu, Moritz Boehme, Jacob Jan Kornet, Uwe Marx, Roland Lauster, Ralf Pörtner, Gerd Lindner
Format: Article
Language:English
Published: MDPI AG 2018-06-01
Series:Bioengineering
Subjects:
full thickness skin equivalents
multi-organ chip
substance permeation
96-well cell culture insert
Online Access:http://www.mdpi.com/2306-5354/5/2/43

Internet

http://www.mdpi.com/2306-5354/5/2/43

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