Genetic predisposition to longer telomere length and risk of childhood, adolescent and adult-onset ependymoma

Genetic predisposition to longer telomere length and risk of childhood, adolescent and adult-onset ependymoma

Abstract Ependymoma is the third most common brain tumor in children, with well-described molecular characterization but poorly understood underlying germline risk factors. To investigate whether genetic predisposition to longer telomere length influences ependymoma risk, we utilized case–control da...

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Bibliographic Details
Main Authors: Chenan Zhang, Quinn T. Ostrom, Eleanor C. Semmes, Vijay Ramaswamy, Helen M. Hansen, Libby Morimoto, Adam J. de Smith, Melike Pekmezci, Zalman Vaksman, Hakon Hakonarson, Sharon J. Diskin, Catherine Metayer, The Glioma International Case-Control Study (GICC), Michael D. Taylor, Joseph L. Wiemels, Melissa L. Bondy, Kyle M. Walsh
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Acta Neuropathologica Communications
Subjects:
Ependymoma
Pediatric cancer
Telomere length
Mendelian randomization
Online Access:http://link.springer.com/article/10.1186/s40478-020-01038-w

Internet

http://link.springer.com/article/10.1186/s40478-020-01038-w

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