Use of Host-like Peptide Motifs in Viral Proteins Is a Prevalent Strategy in Host-Virus Interactions
Viruses interact extensively with host proteins, but the mechanisms controlling these interactions are not well understood. We present a comprehensive analysis of eukaryotic linear motifs (ELMs) in 2,208 viral genomes and reveal that viruses exploit molecular mimicry of host-like ELMs to possibly as...
Main Authors: | Tzachi Hagai, Ariel Azia, M. Madan Babu, Raul Andino |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2014-06-01
|
Series: | Cell Reports |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2211124714003702 |
Similar Items
-
Prediction of HIV-1 virus-host protein interactions using virus and host sequence motifs
by: Tozeren Aydin, et al.
Published: (2009-05-01) -
Virus-host coevolution: common patterns of nucleotide motif usage in Flaviviridae and their hosts.
by: Francisco P Lobo, et al.
Published: (2009-07-01) -
Rapid evolution of virus sequences in intrinsically disordered protein regions.
by: Leonid Gitlin, et al.
Published: (2014-12-01) -
Studies on Host-Virus interaction for Viral Hemorrhagic Septicemia Virus (VHSv)
by: Pore, Adam
Published: (2012) -
Viral Host Range database, an online tool for recording, analyzing and disseminating virus-host interactions
by: Brancotte, B., et al.
Published: (2021)