EphA4 blockers promote axonal regeneration and functional recovery following spinal cord injury in mice.

Upregulation and activation of developmental axon guidance molecules, such as semaphorins and members of the Eph receptor tyrosine kinase family and their ligands, the ephrins, play a role in the inhibition of axonal regeneration following injury to the central nervous system. Previously we have dem...

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Bibliographic Details
Main Authors: Yona Goldshmit, Mark D Spanevello, Sophie Tajouri, Li Li, Fiona Rogers, Martin Pearse, Mary Galea, Perry F Bartlett, Andrew W Boyd, Ann M Turnley
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3172248?pdf=render