Bone marrow mesenchymal stem cell therapy in ischemic stroke: mechanisms of action and treatment optimization strategies

Bone marrow mesenchymal stem cell therapy in ischemic stroke: mechanisms of action and treatment optimization strategies

Animal and clinical studies have confirmed the therapeutic effect of bone marrow mesenchymal stem cells on cerebral ischemia, but their mechanisms of action remain poorly understood. Here, we summarize the transplantation approaches, directional migration, differentiation, replacement, neural circui...

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Bibliographic Details
Main Authors: Guihong Li, Fengbo Yu, Ting Lei, Haijun Gao, Peiwen Li, Yuxue Sun, Haiyan Huang, Qingchun Mu
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2016-01-01
Series:Neural Regeneration Research
Subjects:
nerve regeneration; ischemia/reperfusion injury; animal model; mechanisms of action; clinical application; research progress; genetic modification; angiogenesis; replacement therapy; neural regeneration
Online Access:http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=6;spage=1015;epage=1024;aulast=Li

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http://www.nrronline.org/article.asp?issn=1673-5374;year=2016;volume=11;issue=6;spage=1015;epage=1024;aulast=Li

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