GluN2 Subunit-Dependent Redox Modulation of NMDA Receptor Activation by Homocysteine

GluN2 Subunit-Dependent Redox Modulation of NMDA Receptor Activation by Homocysteine

Homocysteine (HCY) molecule combines distinct pharmacological properties as an agonist of <i>N</i>-methyl-<span style="font-variant: small-caps;">d</span>-aspartate receptors (NMDARs) and a reducing agent. Whereas NMDAR activation by HCY was elucidated, whether the...

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Bibliographic Details
Main Authors: Dmitry A. Sibarov, Sergei I. Boikov, Tatiana V. Karelina, Sergei M. Antonov
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:Biomolecules
Subjects:
homocysteine
thiol
redox modulation
NMDA receptors
glutamate
cysteine
Online Access:https://www.mdpi.com/2218-273X/10/10/1441

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