Preliminary Screening a Potential AChE Inhibitor in Thai Golden Shower (Leguminosae mimosoideae) Extracts

• Main Authors: Jakkaphun Nanuam, Khobkul Nongnutch, Chawanrat Somnuek, Voravit Cheevaporn
• Format: Article
• Language: English
• Published: Thai Society of Higher Eduction Institutes on Environment 2013-07-01
• Series: EnvironmentAsia
• Subjects: AChE inhibitor; ethanolic plant extracts; golden shower (Leguminosae mimosoideae); golden apple snail (Pomacea canaliculata)
• Online Access: http://www.tshe.org/ea/pdf/vol6%20no2-7.pdf

Pesticides are used to control pests of agriculture products in many countries including Thailand. Since they can exert harmful effects not only on target pests but also on other useful organisms, alternative agents are investigated. We studied the capacity of the Thai golden shower (Leguminosae mimosoideae) extracts (root and pod) to inhibit acetyl cholinestarese (AChE) in the golden apple snail (Pomacea canaliculata) as a pest representative. The results showed that the percentage of AChE inhibition increased with increasing in exposure times. The inhibition expressed the same trend in both male and female apple snails. AChE inhibition was higher in extracts from root than from pod. Chromatography-Mass Spectrometer (GC-MS) chromatograms demonstrated anthraquinone, an AChE inhibitor, in extracts of golden shower. Our data indicate that a potential AChE inhibitor tends to accumulate more in the root part than in the pod.