Functional and morphological changes of the mucous membrane of the stomach after long application of proton pump inhibitors

Changes of mucous membrane of rats’ stomach after long term application of proton pump inhibition – Omeprazole. Increase of pepsin concentration, volume and рН in both fasting and basal gastric juice in comparison with the control was observed. It is established that the content of nitrates and nitr...

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Bibliographic Details
Main Authors: M. V. Markina, A. K. Vyatkin, V. P. Lyashenko, A. I. Rudenko
Format: Article
Language:English
Published: Oles Honchar Dnipropetrovsk National University 2010-04-01
Series:Vìsnik Dnìpropetrovsʹkogo Unìversitetu: Serìâ Bìologìâ, Medicina
Online Access:http://medicine.dp.ua/index.php/med/article/view/193
Description
Summary:Changes of mucous membrane of rats’ stomach after long term application of proton pump inhibition – Omeprazole. Increase of pepsin concentration, volume and рН in both fasting and basal gastric juice in comparison with the control was observed. It is established that the content of nitrates and nitrites in gastric juice and in the rats’ mixed saliva after the 12th day of introduction of proton pump inhibitors is 3:1.
ISSN:2310-4155
2312-7295