Penfluridol induces endoplasmic reticulum stress leading to autophagy in pancreatic cancer

Pancreatic cancer is one of the most aggressive and difficult to treat cancers. Experimental and clinical evidence suggests that high basal state autophagy in pancreatic tumors could induce resistance to chemotherapy. Recently, we have demonstrated that penfluridol suppresses pancreatic tumor growth...

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Bibliographic Details
Main Authors: Alok Ranjan, Nadezhda German, Constantinos Mikelis, Kalkunte Srivenugopal, Sanjay K Srivastava
Format: Article
Language:English
Published: IOS Press 2017-05-01
Series:Tumor Biology
Online Access:https://doi.org/10.1177/1010428317705517