A rare case of hepatocellular carcinoma arising from gadoxetate-retaining hepatic adenoma

Hepatocellular adenomas (HCAs) are benign lesions of the liver which can rarely undergo malignant transformation. We report a 26-year-old woman with no underlying liver disease found to have an incidental liver lesion on noncontrast CT during workup for gastric reflux. Follow up MRI revealed a 10 cm...

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Main Authors: Mario A. Cedillo, MD, Joshua Wong, MD, Joseph W. Song, MD, Joseph Liao, MD
Format: Article
Language:English
Published: Elsevier 2020-02-01
Series:Radiology Case Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S1930043319303577
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spelling doaj-11e52b05858748838b1294656982409a2020-11-25T01:17:19ZengElsevierRadiology Case Reports1930-04332020-02-01152141143A rare case of hepatocellular carcinoma arising from gadoxetate-retaining hepatic adenomaMario A. Cedillo, MD0Joshua Wong, MD1Joseph W. Song, MD2Joseph Liao, MD3Corresponding author.; Department of Radiology, Icahn School of Medicine at Mount Sinai Hospital, New York, NY, USADepartment of Radiology, Icahn School of Medicine at Mount Sinai Hospital, New York, NY, USADepartment of Radiology, Icahn School of Medicine at Mount Sinai Hospital, New York, NY, USADepartment of Radiology, Icahn School of Medicine at Mount Sinai Hospital, New York, NY, USAHepatocellular adenomas (HCAs) are benign lesions of the liver which can rarely undergo malignant transformation. We report a 26-year-old woman with no underlying liver disease found to have an incidental liver lesion on noncontrast CT during workup for gastric reflux. Follow up MRI revealed a 10 cm gadoxetate-retaining lesion within the right hepatic lobe with imaging features suggestive of HCA vs focal nodular hyperplasia . Within this lesion was a focus of arterial enhancement with venous washout suggestive of hepatocellular carcinoma (HCC) within HCA, later confirmed at surgical resection. Understanding the imaging characteristics of HCAs as well as their rare ability to undergo malignant transformation is useful in differentiating HCAs from focal nodular hyperplasia. Keywords: Hepatocellular carcionoma, Hepatic adenoma, Inflammatory hepatic adenoma, HCChttp://www.sciencedirect.com/science/article/pii/S1930043319303577
collection DOAJ
language English
format Article
sources DOAJ
author Mario A. Cedillo, MD
Joshua Wong, MD
Joseph W. Song, MD
Joseph Liao, MD
spellingShingle Mario A. Cedillo, MD
Joshua Wong, MD
Joseph W. Song, MD
Joseph Liao, MD
A rare case of hepatocellular carcinoma arising from gadoxetate-retaining hepatic adenoma
Radiology Case Reports
author_facet Mario A. Cedillo, MD
Joshua Wong, MD
Joseph W. Song, MD
Joseph Liao, MD
author_sort Mario A. Cedillo, MD
title A rare case of hepatocellular carcinoma arising from gadoxetate-retaining hepatic adenoma
title_short A rare case of hepatocellular carcinoma arising from gadoxetate-retaining hepatic adenoma
title_full A rare case of hepatocellular carcinoma arising from gadoxetate-retaining hepatic adenoma
title_fullStr A rare case of hepatocellular carcinoma arising from gadoxetate-retaining hepatic adenoma
title_full_unstemmed A rare case of hepatocellular carcinoma arising from gadoxetate-retaining hepatic adenoma
title_sort rare case of hepatocellular carcinoma arising from gadoxetate-retaining hepatic adenoma
publisher Elsevier
series Radiology Case Reports
issn 1930-0433
publishDate 2020-02-01
description Hepatocellular adenomas (HCAs) are benign lesions of the liver which can rarely undergo malignant transformation. We report a 26-year-old woman with no underlying liver disease found to have an incidental liver lesion on noncontrast CT during workup for gastric reflux. Follow up MRI revealed a 10 cm gadoxetate-retaining lesion within the right hepatic lobe with imaging features suggestive of HCA vs focal nodular hyperplasia . Within this lesion was a focus of arterial enhancement with venous washout suggestive of hepatocellular carcinoma (HCC) within HCA, later confirmed at surgical resection. Understanding the imaging characteristics of HCAs as well as their rare ability to undergo malignant transformation is useful in differentiating HCAs from focal nodular hyperplasia. Keywords: Hepatocellular carcionoma, Hepatic adenoma, Inflammatory hepatic adenoma, HCC
url http://www.sciencedirect.com/science/article/pii/S1930043319303577
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