Improvement of cerebellar ataxic gait by injecting Cbln1 into the cerebellum of cbln1-null mice

Abstract Patients and rodents with cerebellar damage display ataxic gaits characterized by impaired coordination of limb movements. Here, gait ataxia in mice with a null mutation of the gene for the cerebellin 1 precursor protein (cbln1-null mice) was investigated by kinematic analysis of hindlimb m...

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Bibliographic Details
Main Authors: Eri Takeuchi, Aya Ito-Ishida, Michisuke Yuzaki, Dai Yanagihara
Format: Article
Language:English
Published: Nature Publishing Group 2018-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-018-24490-0