MEN1 silencing aggravates tumorigenic potential of AR-independent prostate cancer cells through nuclear translocation and activation of JunD and β-catenin

MEN1 silencing aggravates tumorigenic potential of AR-independent prostate cancer cells through nuclear translocation and activation of JunD and β-catenin

Abstract Background Recent studies highlighted the increased frequency of AR-low or -negative prostate cancers (PCas) and the importance of AR-independent mechanisms in driving metastatic castration-resistant PCa (mCRPC) development and progression. Several previous studies have highlighted the invo...

Full description

Bibliographic Details
Main Authors: Yakun Luo, Virginie Vlaeminck-Guillem, Silvère Baron, Sarah Dallel, Chang Xian Zhang, Muriel Le Romancer
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
Prostate cancer
AR-independent cells
MEN1
JunD
β-Catenin
Online Access:https://doi.org/10.1186/s13046-021-02058-7

Internet

https://doi.org/10.1186/s13046-021-02058-7

Similar Items