Human P2Y11 Expression Level Affects Human P2X7 Receptor-Mediated Cell Death

Human P2Y11 Expression Level Affects Human P2X7 Receptor-Mediated Cell Death

Adenosine triphosphate (ATP) is known to induce cell death in T lymphocytes at high extracellular concentrations. CD4+ and CD8+ T lymphocytes have a differential response to ATP, which in mice is due to differences in the P2X7 receptor expression levels. By contrast, we observed that the difference...

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Bibliographic Details
Main Authors: Karin Dreisig, Louise Sund, Maja Wallentin Dommer, Nikolaj Pagh Kristensen, Kim Boddum, Rannveig Viste, Simon Fredholm, Niels Odum, Marja Jäättelä, Søren Skov, Birgitte R. Kornum
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
P2RY11
P2RX7
A740003
Fluo-4
cyclic adenosine monophosphate
purinergic
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01159/full

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