MiR-192-Mediated Positive Feedback Loop Controls the Robustness of Stress-Induced p53 Oscillations in Breast Cancer Cells.
The p53 tumor suppressor protein plays a critical role in cellular stress and cancer prevention. A number of post-transcriptional regulators, termed microRNAs, are closely connected with the p53-mediated cellular networks. While the molecular interactions among p53 and microRNAs have emerged, a syst...
Main Authors: | Richard Moore, Hsu Kiang Ooi, Taek Kang, Leonidas Bleris, Lan Ma |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-12-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4671655?pdf=render |
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