Development of a quantitative bead capture assay for soluble IL-7 receptor alpha in human plasma.

Development of a quantitative bead capture assay for soluble IL-7 receptor alpha in human plasma.

BACKGROUND: IL-7 is an essential cytokine in T-cell development and homeostasis. It binds to the IL-7R receptor, a complex of the IL-7Ralpha (CD127) and common gamma (CD132) chains. There is significant interest in evaluating the expression of CD127 on human T-cells as it often decreased in medical...

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Main Authors: Sylvie Faucher, Angela M Crawley, Wendy Decker, Alice Sherring, Dragica Bogdanovic, Tao Ding, Michele Bergeron, Jonathan B Angel, Paul Sandstrom
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2723935?pdf=render

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