Silibinin alleviates hyperlipidaemia, restores mucin content, modulates TGF-β and fosters apoptosis in experimental rat colon carcinogenesis

The effect of silibinin on lipid profile, colonic mucin content, transforming growth factor beta (TGF-β) expression, cell proliferation and apoptosis in high fat diet fed rats challenged with 1, 2 dimethyl hydrazine (DMH) was investigated. Rats were randomized into six groups. Group 1: Control rats;...

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Bibliographic Details
Main Authors: Sangeetha Nagarajan, Nalini Namasivayam
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Journal of Functional Foods
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464614003314