Aortic Knob Width as an Indicator of Cardiovascular Risk in Chronic Kidney Disease Patients

Introduction: The most common cause of mortality in Chronic Kidney Disease (CKD) patients is due to cardiovascular events. The Aortic Knob Width (AKW) has been found to positively correlate with the severity of coronary artery disease. This study describes the use of chest x-ray in evaluating CKD po...

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Main Authors: JERIN J OVETT, AJAY N BHAT, VENKATRAYA PRABHU
Format: Article
Language:English
Published: JCDR Research and Publications Private Limited 2018-08-01
Series:Journal of Clinical and Diagnostic Research
Subjects:
Online Access:https://jcdr.net/articles/PDF/11898/35942_CE[Ra1]_F(RK)_PF1(PG_SHU)_PN(AP).pdf
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spelling doaj-11be80fbb2334184bcd5e0ef766ffd422020-11-25T02:37:36ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2018-08-01128OC22OC2410.7860/JCDR/2018/35942.11898Aortic Knob Width as an Indicator of Cardiovascular Risk in Chronic Kidney Disease PatientsJERIN J OVETT0 AJAY N BHAT1VENKATRAYA PRABHU2Junior Resident, Department of Medicine, Kasturba Medical College, Mangalore, Karnataka, India.Assistant Professor, Department of Medicine, Kasturba Medical College, Mangalore, Karnataka, India.Professor And Dean, Department of Medicine, Kasturba Medical College, Mangalore, Karnataka, India.Introduction: The most common cause of mortality in Chronic Kidney Disease (CKD) patients is due to cardiovascular events. The Aortic Knob Width (AKW) has been found to positively correlate with the severity of coronary artery disease. This study describes the use of chest x-ray in evaluating CKD population who are at risk for cardiovascular events. Aim: To measure the Aortic Knob Width (AKW) by chest x-ray in CKD patients and compare Aortic knob width with Framinghams’ risk score and other parameters like urea, creatinine, magnesium, calcium, phosphate, albumin, haemoglobin and C-reactive protein. Materials and Methods: A cross sectional study was done between September 2015 and September 2017 in 60 patients belonging to stage 3 to stage 5 CKD. The aortic knob width as measured using chest x-ray was compared with the Framingham’s risk score and other lab parameters like urea, creatinine, magnesium, calcium, phosphate, albumin, haemoglobin and C-reactive protein routinely measured in CKD patients. Statistical package SPSS version 17.0 was used. p<0.05 was considered as significant and Receiver Operating Characteristic(ROC) curves were used to arrive at a cut-off for AKW which correlated with increased cardiovascular risk. Results: The mean AKW was 3.2±0.43 cm. The AKW had a significant positive correlation with Framingham’s 10-year cardiovascular risk scoring (p<0.0001). Using the Receiver Operating Characteristic (ROC) curve, we found that AKW more than 3.1 centimetres corresponds with moderate to high risk as calculated using Framingham’s scoring system with a sensitivity of 82% and specificity of 86%. Karl Pearson’s correlation test showed no significant correlation between AKW and Duration of disease as well as various parameters like urea, creatinine, magnesium, calcium, phosphate, albumin, haemoglobin and C-reactive protein. Conclusion: The findings of the study allow us to use chest x-ray as a screening tool in CKD patients who are at increased risk of adverse cardiovascular events.https://jcdr.net/articles/PDF/11898/35942_CE[Ra1]_F(RK)_PF1(PG_SHU)_PN(AP).pdfchest x-raycoronary artery diseasecreatininescoring
collection DOAJ
language English
format Article
sources DOAJ
author JERIN J OVETT
AJAY N BHAT
VENKATRAYA PRABHU
spellingShingle JERIN J OVETT
AJAY N BHAT
VENKATRAYA PRABHU
Aortic Knob Width as an Indicator of Cardiovascular Risk in Chronic Kidney Disease Patients
Journal of Clinical and Diagnostic Research
chest x-ray
coronary artery disease
creatinine
scoring
author_facet JERIN J OVETT
AJAY N BHAT
VENKATRAYA PRABHU
author_sort JERIN J OVETT
title Aortic Knob Width as an Indicator of Cardiovascular Risk in Chronic Kidney Disease Patients
title_short Aortic Knob Width as an Indicator of Cardiovascular Risk in Chronic Kidney Disease Patients
title_full Aortic Knob Width as an Indicator of Cardiovascular Risk in Chronic Kidney Disease Patients
title_fullStr Aortic Knob Width as an Indicator of Cardiovascular Risk in Chronic Kidney Disease Patients
title_full_unstemmed Aortic Knob Width as an Indicator of Cardiovascular Risk in Chronic Kidney Disease Patients
title_sort aortic knob width as an indicator of cardiovascular risk in chronic kidney disease patients
publisher JCDR Research and Publications Private Limited
series Journal of Clinical and Diagnostic Research
issn 2249-782X
0973-709X
publishDate 2018-08-01
description Introduction: The most common cause of mortality in Chronic Kidney Disease (CKD) patients is due to cardiovascular events. The Aortic Knob Width (AKW) has been found to positively correlate with the severity of coronary artery disease. This study describes the use of chest x-ray in evaluating CKD population who are at risk for cardiovascular events. Aim: To measure the Aortic Knob Width (AKW) by chest x-ray in CKD patients and compare Aortic knob width with Framinghams’ risk score and other parameters like urea, creatinine, magnesium, calcium, phosphate, albumin, haemoglobin and C-reactive protein. Materials and Methods: A cross sectional study was done between September 2015 and September 2017 in 60 patients belonging to stage 3 to stage 5 CKD. The aortic knob width as measured using chest x-ray was compared with the Framingham’s risk score and other lab parameters like urea, creatinine, magnesium, calcium, phosphate, albumin, haemoglobin and C-reactive protein routinely measured in CKD patients. Statistical package SPSS version 17.0 was used. p<0.05 was considered as significant and Receiver Operating Characteristic(ROC) curves were used to arrive at a cut-off for AKW which correlated with increased cardiovascular risk. Results: The mean AKW was 3.2±0.43 cm. The AKW had a significant positive correlation with Framingham’s 10-year cardiovascular risk scoring (p<0.0001). Using the Receiver Operating Characteristic (ROC) curve, we found that AKW more than 3.1 centimetres corresponds with moderate to high risk as calculated using Framingham’s scoring system with a sensitivity of 82% and specificity of 86%. Karl Pearson’s correlation test showed no significant correlation between AKW and Duration of disease as well as various parameters like urea, creatinine, magnesium, calcium, phosphate, albumin, haemoglobin and C-reactive protein. Conclusion: The findings of the study allow us to use chest x-ray as a screening tool in CKD patients who are at increased risk of adverse cardiovascular events.
topic chest x-ray
coronary artery disease
creatinine
scoring
url https://jcdr.net/articles/PDF/11898/35942_CE[Ra1]_F(RK)_PF1(PG_SHU)_PN(AP).pdf
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