YAP enhances autophagic flux to promote breast cancer cell survival in response to nutrient deprivation.

YAP enhances autophagic flux to promote breast cancer cell survival in response to nutrient deprivation.

The Yes-associated protein (YAP), a transcriptional coactivator inactivated by the Hippo tumor suppressor pathway, functions as an oncoprotein in a variety of cancers. However, its contribution to breast cancer remains controversial. This study investigated the role of YAP in breast cancer cells und...

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Bibliographic Details
Main Authors: Qinghe Song, Beibei Mao, Jinbo Cheng, Yuhao Gao, Ke Jiang, Jun Chen, Zengqiang Yuan, Songshu Meng
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4374846?pdf=render

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