Morphogenetic chromatin reorganization aspects at the preleptoten stage of human spermatogenesis
Male germ cells pool forms due to proliferation of germ cells during migration into the embryonic gonads and apoptosis. At the different stages of antenatal development a part of germ сells population in the seminiferous cords is represented by cells at the preleptotene stage of meiosis I. In newbor...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2016-07-01
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| Series: | Andrologiâ i Genitalʹnaâ Hirurgiâ |
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| Online Access: | https://agx.abvpress.ru/jour/article/view/194 |
| Summary: | Male germ cells pool forms due to proliferation of germ cells during migration into the embryonic gonads and apoptosis. At the different stages of antenatal development a part of germ сells population in the seminiferous cords is represented by cells at the preleptotene stage of meiosis I. In newborns and infants a number of gametes at this stage of meiosis varies. Male germ cells enter meiotic development mainly in the puberty period. One of the theories of the unique chromatin condensation at the preleptotene stage (prochromosome) is a lack of special signal molecules responsible for the male gametes development. Another theory is that it is a modification that marks the germ сells capable of meiosis activation. |
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| ISSN: | 2070-9781 |