Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon region

The histo-blood group ABH antigens were first described in humans. These antigens are only present on erythrocytes from great apes and humans, while in more primitive animals they are found in tissues and body fluids. The ABH antigens are mainly distributed in tissues exposed to the external environ...

Full description

Bibliographic Details
Main Authors: Délia Cristina Figueira Aguiar, Vera Lúcia de Souza Barros, Washington Luiz Assunção Pereira, Rosane do Socorro Pompeu de Loiola, Gyselly Cássia Bastos de Matos, João Valsecchi, Tereza Cristina Oliveira Corvelo
Format: Article
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2011-12-01
Series:Memórias do Instituto Oswaldo Cruz.
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000800007&lng=en&tlng=en
id doaj-11ad88af9e564cc5b2716f6695bcd1d2
record_format Article
spelling doaj-11ad88af9e564cc5b2716f6695bcd1d22020-11-24T23:48:50ZengInstituto Oswaldo Cruz, Ministério da SaúdeMemórias do Instituto Oswaldo Cruz.1678-80602011-12-01106893694110.1590/S0074-02762011000800007S0074-02762011000800007Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon regionDélia Cristina Figueira Aguiar0Vera Lúcia de Souza Barros1Washington Luiz Assunção Pereira2Rosane do Socorro Pompeu de Loiola3Gyselly Cássia Bastos de Matos4João Valsecchi5Tereza Cristina Oliveira Corvelo6Universidade Federal do ParáUniversidade Federal do ParáUniversidade Federal Rural da AmazôniaLaboratório Central do EstadoInstituto Evandro ChagasInstituto de Desenvolvimento Sustentável MamirauáUniversidade Federal do ParáThe histo-blood group ABH antigens were first described in humans. These antigens are only present on erythrocytes from great apes and humans, while in more primitive animals they are found in tissues and body fluids. The ABH antigens are mainly distributed in tissues exposed to the external environment and potentially serve as ligands for pathogens or inhibitors of tissue connections. The objective of this paper was two-fold: (i) to determine the presence of Helicobacter sp. in the gastric mucosa of 16 captive and 24 free-living New World monkeys and (ii) to evaluate the presence of histopathological alterations related to bacterial infection and the associated expression of ABH antigens in the tissue. Stomach tissues from 13 species of monkey were assessed using haematoxylin-eosin and modified Gram staining (Hucker) methods. An immunohistochemical analysis of the tissue revealed the presence of infectious bacteria that were characteristic of the genus Helicobacter sp. The results demonstrate that various species of monkey might be naturally infected with the Helicobacter sp. and that there is an increased susceptibility to infection. This study serves as a comparative analysis of infection between human and non-human primates and indicates the presence of a new species of Helicobacter.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000800007&lng=en&tlng=enNew World primatesHelicobacter sp.- ABO blood group systemimmunohistochemistry
collection DOAJ
language English
format Article
sources DOAJ
author Délia Cristina Figueira Aguiar
Vera Lúcia de Souza Barros
Washington Luiz Assunção Pereira
Rosane do Socorro Pompeu de Loiola
Gyselly Cássia Bastos de Matos
João Valsecchi
Tereza Cristina Oliveira Corvelo
spellingShingle Délia Cristina Figueira Aguiar
Vera Lúcia de Souza Barros
Washington Luiz Assunção Pereira
Rosane do Socorro Pompeu de Loiola
Gyselly Cássia Bastos de Matos
João Valsecchi
Tereza Cristina Oliveira Corvelo
Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon region
Memórias do Instituto Oswaldo Cruz.
New World primates
Helicobacter sp.
- ABO blood group system
immunohistochemistry
author_facet Délia Cristina Figueira Aguiar
Vera Lúcia de Souza Barros
Washington Luiz Assunção Pereira
Rosane do Socorro Pompeu de Loiola
Gyselly Cássia Bastos de Matos
João Valsecchi
Tereza Cristina Oliveira Corvelo
author_sort Délia Cristina Figueira Aguiar
title Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon region
title_short Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon region
title_full Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon region
title_fullStr Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon region
title_full_unstemmed Immunodetection of Helicobacter sp. and the associated expression of ABO blood group antigens in the gastric mucosa of captive and free-living New World primates in the Amazon region
title_sort immunodetection of helicobacter sp. and the associated expression of abo blood group antigens in the gastric mucosa of captive and free-living new world primates in the amazon region
publisher Instituto Oswaldo Cruz, Ministério da Saúde
series Memórias do Instituto Oswaldo Cruz.
issn 1678-8060
publishDate 2011-12-01
description The histo-blood group ABH antigens were first described in humans. These antigens are only present on erythrocytes from great apes and humans, while in more primitive animals they are found in tissues and body fluids. The ABH antigens are mainly distributed in tissues exposed to the external environment and potentially serve as ligands for pathogens or inhibitors of tissue connections. The objective of this paper was two-fold: (i) to determine the presence of Helicobacter sp. in the gastric mucosa of 16 captive and 24 free-living New World monkeys and (ii) to evaluate the presence of histopathological alterations related to bacterial infection and the associated expression of ABH antigens in the tissue. Stomach tissues from 13 species of monkey were assessed using haematoxylin-eosin and modified Gram staining (Hucker) methods. An immunohistochemical analysis of the tissue revealed the presence of infectious bacteria that were characteristic of the genus Helicobacter sp. The results demonstrate that various species of monkey might be naturally infected with the Helicobacter sp. and that there is an increased susceptibility to infection. This study serves as a comparative analysis of infection between human and non-human primates and indicates the presence of a new species of Helicobacter.
topic New World primates
Helicobacter sp.
- ABO blood group system
immunohistochemistry
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762011000800007&lng=en&tlng=en
work_keys_str_mv AT deliacristinafigueiraaguiar immunodetectionofhelicobacterspandtheassociatedexpressionofabobloodgroupantigensinthegastricmucosaofcaptiveandfreelivingnewworldprimatesintheamazonregion
AT veraluciadesouzabarros immunodetectionofhelicobacterspandtheassociatedexpressionofabobloodgroupantigensinthegastricmucosaofcaptiveandfreelivingnewworldprimatesintheamazonregion
AT washingtonluizassuncaopereira immunodetectionofhelicobacterspandtheassociatedexpressionofabobloodgroupantigensinthegastricmucosaofcaptiveandfreelivingnewworldprimatesintheamazonregion
AT rosanedosocorropompeudeloiola immunodetectionofhelicobacterspandtheassociatedexpressionofabobloodgroupantigensinthegastricmucosaofcaptiveandfreelivingnewworldprimatesintheamazonregion
AT gysellycassiabastosdematos immunodetectionofhelicobacterspandtheassociatedexpressionofabobloodgroupantigensinthegastricmucosaofcaptiveandfreelivingnewworldprimatesintheamazonregion
AT joaovalsecchi immunodetectionofhelicobacterspandtheassociatedexpressionofabobloodgroupantigensinthegastricmucosaofcaptiveandfreelivingnewworldprimatesintheamazonregion
AT terezacristinaoliveiracorvelo immunodetectionofhelicobacterspandtheassociatedexpressionofabobloodgroupantigensinthegastricmucosaofcaptiveandfreelivingnewworldprimatesintheamazonregion
_version_ 1725484325067030528