Overexpression of PIK3R1 promotes hepatocellular carcinoma progression

Overexpression of PIK3R1 promotes hepatocellular carcinoma progression

Abstract Background Phosphoinositide-3-kinase, regulatory subunit 1 (PIK3R1) could regulate cancer cell proliferation important for cancer cell proliferation; however, its role in Hepatocellular carcinoma (HCC) remains largely unknown. Here, we investigated the role of PIK3R1 in HCC and examined the...

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Bibliographic Details
Main Authors: Xuejun Ai, Lei Xiang, Zhi Huang, Shi Zhou, Shuai Zhang, Tao Zhang, Tianpeng Jiang
Format: Article
Language:English
Published: BMC 2018-11-01
Series:Biological Research
Subjects:
Hepatocellular carcinoma
PIK3R1
Apoptosis
Targeted therapy
Online Access:http://link.springer.com/article/10.1186/s40659-018-0202-7

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