The HTLV-1 Tax protein binding domain of cyclin-dependent kinase 4 (CDK4) includes the regulatory PSTAIRE helix

<p>Abstract</p> <p>Background</p> <p>The Tax oncoprotein of human T-cell leukemia virus type 1 (HTLV-1) is leukemogenic in transgenic mice and induces permanent T-cell growth <it>in vitro</it>. It is found in active CDK holoenzyme complexes from adult T-cell...

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Bibliographic Details
Main Authors: Grassmann Ralph, Müller Birthe, Fraedrich Kirsten
Format: Article
Language:English
Published: BMC 2005-09-01
Series:Retrovirology
Online Access:http://www.retrovirology.com/content/2/1/54