PRF a novel acumen for managing post-Surgical defects after removal of mandibular third molars: A case report

• Main Authors: Aruna Tambuwala, Deepak Kaul, Tofiq Bohra, Shehzad Sheikh
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2014-01-01
• Series: Journal of Head & Neck Physicians and Surgeons
• Subjects: Platelet-rich fibrin; growth factors; complex fibrin matrix; platelet rich plasma; centrifugation; wound healing
• Online Access: http://www.jhnps.org/article.asp?issn=2347-8128;year=2014;volume=2;issue=1;spage=73;epage=80;aulast=Tambuwala;type=0

Platelet-rich fibrin (PRF) or leucocyte- and platelet-rich fibrin (L-PRF) is a second-generation PRP where autologous platelets and leucocytes are present in a complex fibrin matrix to accelerate the healing of soft and hard tissue. A platelet-rich fibrin (PRF) membrane containing bone growth enhancing elements can be stitched over the wound or a graft material or scaffold is placed in the socket of an extracted tooth at the time of extraction. The socket is then directly closed with stitches or covered with a non-resorbable or resorbable membrane and sutured. It is known that platelets are involved in the process of wound healing through blood clot formation and release of that promote and maintain the wound healing. In this article we have discussed a case treated with PRF after surgical removal of mandibular third molar.