Synthesis and biological activities of the respiratory chain inhibitor aurachin D and new ring versus chain analogues

Aurachins are myxobacterial 3-farnesyl-4(1H)-quinolone derived compounds initially described as respiratory chain inhibitors, more specifically as inhibitors of various cytochrome complexes. They are also known as potent antibiotic compounds. We describe herein the first synthesis of aurachin D thro...

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Bibliographic Details
Main Authors: Xu-Wen Li, Jennifer Herrmann, Yi Zang, Philippe Grellier, Soizic Prado, Rolf Müller, Bastien Nay
Format: Article
Language:English
Published: Beilstein-Institut 2013-07-01
Series:Beilstein Journal of Organic Chemistry
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Online Access:https://doi.org/10.3762/bjoc.9.176

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