Interferon functional analog activates antiviral Jak/Stat signaling through integrin in an arthropod

Summary: Drosophila Vago is a small antiviral peptide. Its ortholog in Culex mosquito was found to be an interferon-like cytokine that limits virus replication through activating Jak/Stat signaling. However, this activation is independent of Domeless, the sole homolog of vertebrate type I cytokine r...

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Bibliographic Details
Main Authors: Jie Gao, Bao-Rui Zhao, Hui Zhang, Yan-Lin You, Fang Li, Xian-Wei Wang
Format: Article
Language:English
Published: Elsevier 2021-09-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124721012158