The age-dependent decline of the extracellular thiol-disulfide balance and its role in SARS-CoV-2 infection

The age-dependent decline of the extracellular thiol-disulfide balance and its role in SARS-CoV-2 infection

SARS–CoV-2 (COVID-19) infection can cause a severe respiratory distress syndrome. The risk of severe manifestations and mortality characteristically increase in the elderly and in the presence of non-COVID-19 comorbidity. We and others previously demonstrated that the low molecular weight (LMW) and...

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Bibliographic Details
Main Authors: Daniela Giustarini, Annalisa Santucci, Desirée Bartolini, Francesco Galli, Ranieri Rossi
Format: Article
Language:English
Published: Elsevier 2021-05-01
Series:Redox Biology
Subjects:
SARS-CoV-2
COVID-19
Spike S protein
ACE-2 receptor
Aging
Oxidative stress
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231721000501

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