A new peptide ligand for targeting human carbonic anhydrase IX, identified through the phage display technology.

A new peptide ligand for targeting human carbonic anhydrase IX, identified through the phage display technology.

<h4>Unlabelled</h4>Carbonic anhydrase IX (CAIX) is a transmembrane enzyme found to be overexpressed in various tumors and associated with tumor hypoxia. Ligands binding this target may be used to visualize hypoxia, tumor manifestation or treat tumors by endoradiotherapy.<h4>Methods...

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Bibliographic Details
Main Authors: Vasileios Askoxylakis, Regine Garcia-Boy, Shoaib Rana, Susanne Krämer, Ulrike Hebling, Walter Mier, Annette Altmann, Annette Markert, Jürgen Debus, Uwe Haberkorn
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21209841/pdf/?tool=EBI

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