Integrating between-host transmission and within-host immunity to analyze the impact of varicella vaccination on zoster

Integrating between-host transmission and within-host immunity to analyze the impact of varicella vaccination on zoster

Varicella-zoster virus (VZV) causes chickenpox and reactivation of latent VZV causes herpes zoster (HZ). VZV reactivation is subject to the opposing mechanisms of declining and boosted VZV-specific cellular mediated immunity (CMI). A reduction in exogenous re-exposure ‘opportunities’ through univers...

Full description

Bibliographic Details
Main Authors: Benson Ogunjimi, Lander Willem, Philippe Beutels, Niel Hens
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-07-01
Series:eLife
Subjects:
varicella
zoster
shingles
vaccination
boosting
modeling
Online Access:https://elifesciences.org/articles/07116

Similar Items

Similar Items