Preventing Complications from High-Dose Rate Brachytherapy when Treating Mobile Tongue Cancer via the Application of a Modular Lead-Lined Spacer.

PURPOSE:To point out the advantages and drawbacks of high-dose rate brachytherapy in the treatment of mobile tongue cancer and indicate the clinical importance of modular lead-lined spacers when applying this technique to patients. METHODS:First, all basic steps to construct the modular spacer are s...

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Bibliographic Details
Main Authors: Shumei Murakami, Rinus G Verdonschot, Naoya Kakimoto, Iori Sumida, Masateru Fujiwara, Kazuhiko Ogawa, Souhei Furukawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4851388?pdf=render
Description
Summary:PURPOSE:To point out the advantages and drawbacks of high-dose rate brachytherapy in the treatment of mobile tongue cancer and indicate the clinical importance of modular lead-lined spacers when applying this technique to patients. METHODS:First, all basic steps to construct the modular spacer are shown. Second, we simulate and evaluate the dose rate reduction for a wide range of spacer configurations. RESULTS:With increasing distance to the source absorbed doses dropped considerably. Significantly more shielding was obtained when lead was added to the spacer and this effect was most pronounced on shorter (i.e. more clinically relevant) distances to the source. CONCLUSIONS:The modular spacer represents an important addition to the planning and treatment stages of mobile tongue cancer using HDR-ISBT.
ISSN:1932-6203