A Large Animal Model of Right Ventricular Failure due to Chronic Thromboembolic Pulmonary Hypertension: A Focus on Function

A Large Animal Model of Right Ventricular Failure due to Chronic Thromboembolic Pulmonary Hypertension: A Focus on Function

Chronic thromboembolic pulmonary hypertension (CTEPH) is a debilitating disease that progresses to right ventricular (RV) failure and death if left untreated. Little is known regarding the progression of RV failure in this disease, greatly limiting effective prognoses, and therapeutic interventions....

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Bibliographic Details
Main Authors: Ashley Mulchrone, Heidi B. Kellihan, Omid Forouzan, Timothy A. Hacker, Melissa L. Bates, Christopher J. Francois, Naomi C. Chesler
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-01-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
pulmonary embolization
pulmonary hemodynamics
right ventricular afterload
effective arterial elastance (Ea)
pulmonary vascular resistance (PVR)
Online Access:https://www.frontiersin.org/article/10.3389/fcvm.2018.00189/full

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