Changes of the ultrastructure and microcirculation of bladder wall in patients with non-invasive types of cancer

• Main Authors: V. N. Pavlov, A. A. Kazihinurov, V. N. Krupin, O. S. Streltsova, V. Z. Galimzyanov, A. R. Zagitov, R. R. Ishemgulov, A. T. Mustafin, Ye. V. Zagaynova, Ye. B. Kiseleva
• Format: Article
• Language: Russian
• Published: ABV-press 2020-02-01
• Series: Onkourologiâ
• Online Access: https://oncourology.abvpress.ru/oncur/article/view/1042

Bladder cancer relapses are associated with diffuse pattern of neoplastic changes in the mucous layer of the bladder; treatment efficacy depends on the degree of structural alterations in the bladder wall.Materials and methods: for evaluation of microcirculation characteristics and structural alterations of mucous layer of the bladder we have used laser analyzer of capillary blood circulation («ЛАКК-01» produced by НПП «ЛАЗМА», Russia) and compact mobile optic tomograph (ИПФ РАН, Russia).Results: conducted researches have shown alterations affecting both epithelial and submucous layers with their microcirculatory bed in perifocal to bladder tumor tissues.Conclusions: complimentary application of laser Doppler flowmeter and compact mobile optic tomograph allows defining the type and extent of pathologic process in the bladder wall in superficial tumors and choosing optimal method of correction.