Silencing of ANGPTL8 Alleviates Insulin Resistance in Trophoblast Cells

Silencing of ANGPTL8 Alleviates Insulin Resistance in Trophoblast Cells

This study aims to investigate the effect of angiopoietin like 8 (ANGPTL8) on gestational diabetes mellitus (GDM) and insulin resistance (IR). The GDM model was induced by high fat diet in mice, and IR was observed. The expression and secretion of ANGPTL8 were promoted in placenta of GDM mice. IR wa...

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Bibliographic Details
Main Authors:	Yu Bai, Qiang Du, Le Zhang, Ling Li, Nana Wang, Bo Wu, Ping Li
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-06-01
Series:	Frontiers in Endocrinology
Subjects:	gestational diabetes mellitus insulin resistance trophoblast cells angiopoietin like 8 c-Jun N-terminal kinase
Online Access:	https://www.frontiersin.org/articles/10.3389/fendo.2021.635321/full

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