Neoadjuvant irradiation of retroperitoneal soft tissue sarcoma with ions (Retro-Ion): study protocol for a randomized phase II pilot trial

Neoadjuvant irradiation of retroperitoneal soft tissue sarcoma with ions (Retro-Ion): study protocol for a randomized phase II pilot trial

Abstract Background Following surgery for soft tissue sarcoma of the retroperitoneum, the predominant pattern of failure is local recurrence, which remains the main cause of death. Radiotherapy is utilized to reduce recurrence rates but the efficacy of this strategy has not been definitely establish...

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Main Authors: K. Seidensaal, M. Kieser, A. Hommertgen, C. Jaekel, S. B. Harrabi, K. Herfarth, G. Mechtesheimer, B. Lehner, M. Schneider, H. Nienhueser, S. Fröhling, G. Egerer, J. Debus, M. Uhl
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Trials
Subjects:
Retroperitoneal soft tissue sarcoma
Carbon ion therapy
Proton therapy
Irradiation
Randomized trial
Hypofractionation
Online Access:https://doi.org/10.1186/s13063-021-05069-z

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