A multiscale study on the mechanisms of spatial organization in ligand-receptor interactions on cell surfaces
The binding of cell surface receptors with extracellular ligands triggers distinctive signaling pathways, leading into the corresponding phenotypic variation of cells. It has been found that in many systems, these ligand-receptor complexes can further oligomerize into higher-order structures. This l...
Main Authors: | Zhaoqian Su, Kalyani Dhusia, Yinghao Wu |
---|---|
Format: | Article |
Language: | English |
Published: |
Elsevier
2021-01-01
|
Series: | Computational and Structural Biotechnology Journal |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S2001037021000969 |
Similar Items
-
A computational model for understanding the oligomerization mechanisms of TNF receptor superfamily
by: Zhaoqian Su, et al.
Published: (2020-01-01) -
Pharmacological Profiles of Oligomerized μ-Opioid Receptors
by: Ing-Kang Ho, et al.
Published: (2013-10-01) -
Understanding Ligand Binding to G-Protein Coupled Receptors Using Multiscale Simulations
by: Mercedes Alfonso-Prieto, et al.
Published: (2019-05-01) -
Using Coarse-Grained Simulations to Characterize the Mechanisms of Protein–Protein Association
by: Kalyani Dhusia, et al.
Published: (2020-07-01) -
Kinetic analysis of Fcγ receptor and T cell receptor interacting with respective ligands
by: Jiang, Ning
Published: (2009)