Selective Inhibition of Histone Deacetylation in Melanoma Increases Targeted Gene Delivery by a Bacteriophage Viral Vector

Selective Inhibition of Histone Deacetylation in Melanoma Increases Targeted Gene Delivery by a Bacteriophage Viral Vector

The previously developed adeno-associated virus/phage (AAVP) vector, a hybrid between M13 bacteriophage (phage) viruses that infect bacteria only and human Adeno-Associated Virus (AAV), is a promising tool in targeted gene therapy against cancer. AAVP can be administered systemically and made tissue...

Full description

Bibliographic Details
Main Authors: Samuel Campbell, Keittisak Suwan, Sajee Waramit, Eric Ofori Aboagye, Amin Hajitou
Format: Article
Language:English
Published: MDPI AG 2018-04-01
Series:Cancers
Subjects:
bacteriophage
C1A
targeted cancer gene therapy
HDAC inhibitors
HDAC6
Online Access:http://www.mdpi.com/2072-6694/10/4/125

Internet

http://www.mdpi.com/2072-6694/10/4/125

Similar Items