Recurrent aseptic meningitis in association with Kikuchi-Fujimoto disease: case report and literature review

<p>Abstract</p> <p>Background</p> <p>Kikuchi Fujimoto disease (KFD), or histiocytic necrotising lymphadenitis, is a benign and self-limiting condition characterised by primarily affecting the cervical lymph nodes. Recurrent aseptic meningitis in association with KFD is...

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Bibliographic Details
Main Authors: Komagamine Tomoko, Nagashima Takahide, Kojima Masaru, Kokubun Norito, Nakamura Toshiki, Hashimoto Kenich, Kimoto Kazuhito, Hirata Koichi
Format: Article
Language:English
Published: BMC 2012-09-01
Series:BMC Neurology
Subjects:
SLE
Online Access:http://www.biomedcentral.com/1471-2377/12/112
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Summary:<p>Abstract</p> <p>Background</p> <p>Kikuchi Fujimoto disease (KFD), or histiocytic necrotising lymphadenitis, is a benign and self-limiting condition characterised by primarily affecting the cervical lymph nodes. Recurrent aseptic meningitis in association with KFD is extremely rare and remains a diagnostic challenge.</p> <p>Case presentation</p> <p>We report a 28-year-old man who presented 7 episodes of aseptic meningitis associated with KFD over the course of 7 years. Histopathological findings of enlarged lymph nodes led to the diagnosis of KFD. The patient’s headache and lymphadenopathy spontaneously resolved without any sequelae.</p> <p>Conclusions</p> <p>A diagnosis of KFD should be considered when enlarged cervical lymph nodes are observed in patients with recurrent aseptic meningitis. A long-term prognosis remains uncertain, and careful follow-up is preferred.</p>
ISSN:1471-2377