Vascular relaxation induced by C-type natriuretic peptide involves the ca2+/NO-synthase/NO pathway.

<h4>Aims</h4>C-type natriuretic peptide (CNP) and nitric oxide (NO) are endothelium-derived factors that play important roles in the regulation of vascular tone and arterial blood pressure. We hypothesized that NO produced by the endothelial NO-synthase (NOS-3) contributes to the relaxat...

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Bibliographic Details
Main Authors: Fernanda A Andrade, Carolina B A Restini, Marcella D Grando, Leandra N Z Ramalho, Lusiane M Bendhack
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24787693/pdf/?tool=EBI