A Case of Multiple Myeloma Misdiagnosed as Seronegative Rheumatoid Arthritis and Review of Relevant Literature

A Case of Multiple Myeloma Misdiagnosed as Seronegative Rheumatoid Arthritis and Review of Relevant Literature

Multiple myeloma (MM) is a malignant plasma cell proliferation producing large numbers of monoclonal immunoglobulins. Typical MM symptoms include anemia, renal failure, hypercalcemia, and bone pain. Atypical symptoms have rarely been reported in the literature. We report a case of a 58-year-old male...

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Main Authors: Scott Schoninger, Yamen Homsi, Alexandra Kreps, Natasa Milojkvovic
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Case Reports in Rheumatology
Online Access:http://dx.doi.org/10.1155/2018/9746241
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spelling doaj-11511a59a426476cb6cf2d275f599d192020-11-25T00:47:13ZengHindawi LimitedCase Reports in Rheumatology2090-68892090-68972018-01-01201810.1155/2018/97462419746241A Case of Multiple Myeloma Misdiagnosed as Seronegative Rheumatoid Arthritis and Review of Relevant LiteratureScott Schoninger0Yamen Homsi1Alexandra Kreps2Natasa Milojkvovic3College of Medicine, SUNY Downstate Medical Center, 450 Clarkson Avenue, Brooklyn, NY 11203, USADivision of Rheumatology, SUNY Downstate Medical Center, 450 Clarkson Avenue Box 42, Brooklyn, NY 11203, USADivision of Rheumatology, SUNY Downstate Medical Center, 450 Clarkson Avenue Box 42, Brooklyn, NY 11203, USADivision of Hematology, University of Arkansas for Medical Sciences, 4301 West Markham Street, Little Rock, Arkansas 72205, USAMultiple myeloma (MM) is a malignant plasma cell proliferation producing large numbers of monoclonal immunoglobulins. Typical MM symptoms include anemia, renal failure, hypercalcemia, and bone pain. Atypical symptoms have rarely been reported in the literature. We report a case of a 58-year-old male who presented with symmetrical inflammatory polyarthritis and was misdiagnosed with seronegative rheumatoid arthritis (RA). After failing many RA treatments and with further workup, the diagnosis of MM was made. This rare manifestation of MM carries a diagnostic challenge and causes a significant delay in treating such patients. Here, we report this unusual initial presentation with review of several cases in the English literature describing similar presentations.http://dx.doi.org/10.1155/2018/9746241
collection DOAJ
language English
format Article
sources DOAJ
author Scott Schoninger
Yamen Homsi
Alexandra Kreps
Natasa Milojkvovic
spellingShingle Scott Schoninger
Yamen Homsi
Alexandra Kreps
Natasa Milojkvovic
A Case of Multiple Myeloma Misdiagnosed as Seronegative Rheumatoid Arthritis and Review of Relevant Literature
Case Reports in Rheumatology
author_facet Scott Schoninger
Yamen Homsi
Alexandra Kreps
Natasa Milojkvovic
author_sort Scott Schoninger
title A Case of Multiple Myeloma Misdiagnosed as Seronegative Rheumatoid Arthritis and Review of Relevant Literature
title_short A Case of Multiple Myeloma Misdiagnosed as Seronegative Rheumatoid Arthritis and Review of Relevant Literature
title_full A Case of Multiple Myeloma Misdiagnosed as Seronegative Rheumatoid Arthritis and Review of Relevant Literature
title_fullStr A Case of Multiple Myeloma Misdiagnosed as Seronegative Rheumatoid Arthritis and Review of Relevant Literature
title_full_unstemmed A Case of Multiple Myeloma Misdiagnosed as Seronegative Rheumatoid Arthritis and Review of Relevant Literature
title_sort case of multiple myeloma misdiagnosed as seronegative rheumatoid arthritis and review of relevant literature
publisher Hindawi Limited
series Case Reports in Rheumatology
issn 2090-6889
2090-6897
publishDate 2018-01-01
description Multiple myeloma (MM) is a malignant plasma cell proliferation producing large numbers of monoclonal immunoglobulins. Typical MM symptoms include anemia, renal failure, hypercalcemia, and bone pain. Atypical symptoms have rarely been reported in the literature. We report a case of a 58-year-old male who presented with symmetrical inflammatory polyarthritis and was misdiagnosed with seronegative rheumatoid arthritis (RA). After failing many RA treatments and with further workup, the diagnosis of MM was made. This rare manifestation of MM carries a diagnostic challenge and causes a significant delay in treating such patients. Here, we report this unusual initial presentation with review of several cases in the English literature describing similar presentations.
url http://dx.doi.org/10.1155/2018/9746241
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