Spatiotemporal control of cell–cell reversible interactions using molecular engineering

Reversible manipulation of cell-cell interactions has potential applications in basic research and cell-based therapy. Here the authors control cell-cell adhesion in vitrowith light, by modifying the surface sugars of cells to display β-cyclodextrin, which recognises one isoform of light-isomerizabl...

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Main Authors:	Peng Shi, Enguo Ju, Zhengqing Yan, Nan Gao, Jiasi Wang, Jianwen Hou, Yan Zhang, Jinsong Ren, Xiaogang Qu
Format:	Article
Language:	English
Published:	Nature Publishing Group 2016-10-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/ncomms13088

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spelling	doaj-114d215b6eaf46bbb46168dbe2cb2ff12021-05-11T10:54:14ZengNature Publishing GroupNature Communications2041-17232016-10-01711910.1038/ncomms13088Spatiotemporal control of cell–cell reversible interactions using molecular engineeringPeng Shi0Enguo Ju1Zhengqing Yan2Nan Gao3Jiasi Wang4Jianwen Hou5Yan Zhang6Jinsong Ren7Xiaogang Qu8Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of SciencesLaboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of SciencesLaboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of SciencesLaboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of SciencesLaboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of SciencesUniversity of Chinese Academy of SciencesCollege of life science, Jilin UniversityLaboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of SciencesLaboratory of Chemical Biology and State Key Laboratory of Rare Earth Resource Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of SciencesReversible manipulation of cell-cell interactions has potential applications in basic research and cell-based therapy. Here the authors control cell-cell adhesion in vitrowith light, by modifying the surface sugars of cells to display β-cyclodextrin, which recognises one isoform of light-isomerizable azobenzene linkers.https://doi.org/10.1038/ncomms13088
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Peng Shi Enguo Ju Zhengqing Yan Nan Gao Jiasi Wang Jianwen Hou Yan Zhang Jinsong Ren Xiaogang Qu
spellingShingle	Peng Shi Enguo Ju Zhengqing Yan Nan Gao Jiasi Wang Jianwen Hou Yan Zhang Jinsong Ren Xiaogang Qu Spatiotemporal control of cell–cell reversible interactions using molecular engineering Nature Communications
author_facet	Peng Shi Enguo Ju Zhengqing Yan Nan Gao Jiasi Wang Jianwen Hou Yan Zhang Jinsong Ren Xiaogang Qu
author_sort	Peng Shi
title	Spatiotemporal control of cell–cell reversible interactions using molecular engineering
title_short	Spatiotemporal control of cell–cell reversible interactions using molecular engineering
title_full	Spatiotemporal control of cell–cell reversible interactions using molecular engineering
title_fullStr	Spatiotemporal control of cell–cell reversible interactions using molecular engineering
title_full_unstemmed	Spatiotemporal control of cell–cell reversible interactions using molecular engineering
title_sort	spatiotemporal control of cell–cell reversible interactions using molecular engineering
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2016-10-01
description	Reversible manipulation of cell-cell interactions has potential applications in basic research and cell-based therapy. Here the authors control cell-cell adhesion in vitrowith light, by modifying the surface sugars of cells to display β-cyclodextrin, which recognises one isoform of light-isomerizable azobenzene linkers.
url	https://doi.org/10.1038/ncomms13088
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Spatiotemporal control of cell–cell reversible interactions using molecular engineering

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