In vitro-in vivo evaluation of fast-dissolving tablets containing solid dispersion of pioglitazone hydrochloride

In vitro-in vivo evaluation of fast-dissolving tablets containing solid dispersion of pioglitazone hydrochloride

Investigation of in vitro/in vivo behavior of fast-dissolving tablets containing solid dispersions of pioglitazone hydrochloride (PIO) is the focus of the present research work. The effect of various hydrophilic polymers on the aqueous solubility of PIO was studied. Poly vinyl pyrrolidine K 30 (PVPK...

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Bibliographic Details
Main Authors: Vinay Pandit, Roopa S Pai, Kusum Devi, Sarasija Suresh
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2012-01-01
Series:Journal of Advanced Pharmaceutical Technology & Research
Subjects:
Dissolution profile
hydrophilic carriers
kneading method
solubility
solid dispersions
Online Access:http://www.japtr.org/article.asp?issn=2231-4040;year=2012;volume=3;issue=3;spage=160;epage=170;aulast=Pandit

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