Anti-Biofilm and Immunomodulatory Activities of Peptides That Inhibit Biofilms Formed by Pathogens Isolated from Cystic Fibrosis Patients

Anti-Biofilm and Immunomodulatory Activities of Peptides That Inhibit Biofilms Formed by Pathogens Isolated from Cystic Fibrosis Patients

Cystic fibrosis (CF) patients often acquire chronic respiratory tract infections due to Pseudomonas aeruginosa and Burkholderia cepacia complex (Bcc) species. In the CF lung, these bacteria grow as multicellular aggregates termed biofilms. Biofilms demonstrate increased (adaptive) resistance to conv...

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Bibliographic Details
Main Authors: César de la Fuente-Núñez, Sarah C. Mansour, Zhejun Wang, Lucy Jiang, Elena B.M. Breidenstein, Melissa Elliott, Fany Reffuveille, David P. Speert, Shauna L. Reckseidler-Zenteno, Ya Shen, Markus Haapasalo, Robert E.W. Hancock
Format: Article
Language:English
Published: MDPI AG 2014-10-01
Series:Antibiotics
Subjects:
anti-biofilm
immunomodulation
peptides
antibiotic-resistance
cystic fibrosis
Online Access:http://www.mdpi.com/2079-6382/3/4/509

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