Disrupted Thalamus White Matter Anatomy and Posterior Default Mode Network Effective Connectivity in Amnestic Mild Cognitive Impairment

Disrupted Thalamus White Matter Anatomy and Posterior Default Mode Network Effective Connectivity in Amnestic Mild Cognitive Impairment

Alzheimer’s disease (AD) and its prodromal state amnestic mild cognitive impairment (aMCI) are characterized by widespread abnormalities in inter-areal white matter fiber pathways and parallel disruption of default mode network (DMN) resting state functional and effective connectivity. In healthy su...

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Bibliographic Details
Main Authors: Thomas Alderson, Elizabeth Kehoe, Liam Maguire, Dervla Farrell, Brian Lawlor, Rose A. Kenny, Declan Lyons, Arun L. W. Bokde, Damien Coyle
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-11-01
Series:Frontiers in Aging Neuroscience
Subjects:
diffusion MRI
tractography
effective connectivity
Alzheimer’s disease
mild cognitive impairment
default mode network
Online Access:http://journal.frontiersin.org/article/10.3389/fnagi.2017.00370/full

Internet

http://journal.frontiersin.org/article/10.3389/fnagi.2017.00370/full

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