RNA-on-X 1 and 2 in Drosophila melanogaster fulfill separate functions in dosage compensation.

RNA-on-X 1 and 2 in Drosophila melanogaster fulfill separate functions in dosage compensation.

In Drosophila melanogaster, the male-specific lethal (MSL) complex plays a key role in dosage compensation by stimulating expression of male X-chromosome genes. It consists of MSL proteins and two long noncoding RNAs, roX1 and roX2, that are required for spreading of the complex on the chromosome an...

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Bibliographic Details
Main Authors:	Maria Kim, Marie-Line Faucillion, Jan Larsson
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2018-12-01
Series:	PLoS Genetics
Online Access:	https://doi.org/10.1371/journal.pgen.1007842

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